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Manipur Univ


Dr Md Hamidur Rahaman

Designation: Assistant Professor

Specialization: Biophysical Chemistry, Molecular Biology, Molecular Dynamics

Contact: +91-9863518139

Email: rahamanh [AT] manipuruniv.ac.in, hamidur2006 [AT] gmail.com

MSc, JRF, Ph.D.

Website: http://manipuruniv.ac.in/faculty/75

Faculty Details Faculty List

RESUME

 

MD. HAMIDUR RAHAMAN, PhD

Assistant Professor

Department of Biotechnology

Manipur University

Canchipur, Manipur, India-795003.

Web of Science Researcher ID: ABE-4554-2021

Orcid ID: 0000-0001-5998-177X

Scopus ID: 42361511700

 

Personnel details:

S/O Md Muhibur Rahaman & Banu Begum

Date of birth: 01/04/1977

Address: Thoubal Moijing Meena Bazar, Thoubal, Manipur, India-795138

 

 

Professional training and research experiences

Academic Qualifications (Graduation onwards):


 

Name of the examination/Degree

Subjects

Area of specialization

Name of Institute/ University/ Board

Year of passing

Percentage/ Grade

BSc (Hons)

Chemistry, Botany, Zoology

Chemistry

Aligarh Muslim University

1998

64.6%

MSc

Protein biochemistry, Mol. Biology, Immunology

Biotechnology

Aligarh Muslim University

2002

60.3%

CSIR-UGC JRF

 

Life Sciences

CSIR-HRDG

June, 2003

 

PhD

 

Protein Biochemistry

CIRBSC, Jamia Millia Islamia

2009

 

 

Employment History:

 

Period (Year)

Name of the examination/Degree/ Post as applicable

Area of specialization/ Subjects

Name of Institute/ University/

Number of Journal Publications

2009-02-21 to 2009-12-31

Pos-doctoral Fellow

Protein Chemistry

Umea University, Sweden

1

2010 -03-25 to 2012-02-29

Post-doctoral Fellow

Physiology and Biochemistry

University of Pennsylvania, USA

1

2012-03-01upto now

Assistant Professor

Biotechnology

Manipur University, Canchipur, Manipur, India

14

 

 

 


 

 

List of publications:

 

  1. The Med8, Med18 and Med20 subunits of the Mediator head domain are interdependent on each other for folding and complex formation. ZakiShaikhibrahim, HamidurRahaman, PernillaWittung-Stafshede and Stefan Björklund PNAS, 2009 Dec; 106(49): 20728–20733.

  1. Sequence and stability of the goat cytochrome c. Hamidur Rahaman, Md Khurshid Alam Khan, Md. Imtaiyaz Hassan, Mohd. Wahid, S. Baskar Singh, Tej P. Singh, Ali Akbar Moosavi-Movahedi and Faizan Ahmad, Biophys Chem. 2008 Nov;138(1-2):23-8.

  1. A single mutation induces molten globule formation and a drastic destabilization of wild type Cytochrome c. Md. Khurshid Alam Khan, Utpal Das, Hamidur Rahaman, Md. Imtaiyaz Hassan, Alagiri Srinivasan, Tej P. Singh, and Faizan Ahmad. J Biol. Inorg Chem. 2009 Jun;14(5):751-60.

  1. Conformational and Thermodynamic Characterization of the Premolten Globule State Occurring during Unfolding of Molten Globule State of Cytochrome-c by Lithium Chloride. Md. Khurshid Alam Khan,Hamidur Rahaman, Utpal Das, Md. Imtaiyaz Hassan, A. Srinivasan,Tej P. Singh, Ali A. Moosavi-Movahedi, and Faizan Ahmad. J Biol Inorg Chem. 2010;15(8):1319-29.

  1. Conformational and Thermodynamic Stability of Premolten and Molten Globule States of Mammalian Cytochromes-c". Md Khurshid Alam Khana, Hamidur Rahaman and Faizan Ahmad. Metallomics. 2011 Apr;3(4):327-38.

  1. Increased Phospholipase A2 Activity with Phosphorylation ofPeroxiredoxin 6 Requires a Conformational Change in the Protein. HamidurRahaman, Suiping Zhou, Chandra Dodia, Sheldon I. Feinstein,Shaohui Huang, David Speicher, and Aron B. Fisher. Biochemistry, 2012; 51, 5521−5530.

  1. Evidence of non-coincidence of normalized sigmoidal curves of two different structural properties for two-state protein folding/unfolding. HamidurRahaman, Md. KhurshidAlam Khan, Md. Imtaiyaz Hassan, Asimul Islam and Faizan Ahmad, Journal of Chemical Thermodynamics, 2013:58, 351-358.

  1. Heterogeneity of Equilibrium Molten Globule state of Cytochrome c induced by Weak Salts Denaturants under physiological condition. HamidurRahaman, Md Khurshid Alam Khan, Imtaiyaz Hassan, Asimul Islam, Ali A. Moosavi-Movahedi and Faizan Ahmad. PlosOne. April, 2015.DOI:10.1371/journal.pone. 0120465.

  1. Understanding structural basis for redox regulation of Peroxiredoxin 6 using in silico approach. Rimpy Kaur Chowhan, Upendra Bhele, Hamidur Rahaman, Laishram Rajendrakumar Singh. Journal of Protein and Proteomics, 8(4), 2017, 195-204.

  1. ISSR marker based population genetic study of Melocanna baccifera (Roxb.) Kurz: a commercially important bamboo of Manipur, North-East India. H Nilkanta, T Amom, L Tikendra, H Rahaman, P Nongdam. Scientifica 2017.

  1. Evaluation of genetic relationship between 15 bamboo species of North-East India based on ISSR marker analysis. T Amom, L Tikendra, H Rahaman, A Potshangbam, P Nongdam. Molecular Biology Research Communications 7 (1), 7.

  1. Hyperoxidation of Peroxiredoxin 6 Induces Alteration from Dimeric to Oligomeric State Sharifun Shahnaj; Rimpy Kaur Chowhan; Potshangbam Angamba Meetei; Pushpa Kakchingtabam; Khundrakpam Herojit Singh; Laishram Rajendrakumar Singh; Potshangbam Nongdam; Aron B. Fisher; Hamidur Rahaman, Antioxidants, 8(2), 2019, 33.

 

  1. Efficiency of RAPD, ISSR, iPBS, SCoT and phytochemical markers in the genetic relationship study of five native and economical important bamboos of North-East India Thoungamba Amom, Leimapokpam Tikendra, Nandeibam Apana, Moirangthem Goutam, Paonam Sonia, Arunkumar Singh Koijam, Angamba Meetei Potshangbam, Hamidur Rahaman, Potshangbam Nongdam. Phytochemistry 174, 112330, 2019

  1. The anti-oxidant enzyme, Prdx6 might have cis-acting regulatory sequence (s) Sharifun Shahnaj, Angamba Meetei Potshangbam, Rimpy Kaur Chowhan, Zahoor Ahmad Parray, Pushpa Kakchingtabam, Anju Kumari, Asimul Islam, Aslam Khan, Laishram Rajendrakumar Singh, Hamidur Rahaman, International Journal of Biological Macromolecules, 149, 2020, 1139-1150.

  1. N-Acetylaspartate Is an Important Brain Osmolyte. Marina Warepam, Khurshid Ahmad, Safikur Rahman, Hamidur Rahaman, Kritika Kumari, Laishram Rajendrakumar Singh, Biomolecules, 2020, 10 (2), 286.

  1. Effect of Bi contents on key physical properties of NiO NPs synthesized by flash combustion process and their cytotoxicity studies for biomedical applications. Aslam Khan, Mohd Shkir, Essam H Ibrahim, Mona Kilany, S AlFaify, MA Sayeed, Ahmed Mohamed El-Toni, Ali Aldalbahi, Hamidur Rahaman, Mohammad Mairaj Siddiquei, Ceramics International, 2020.

  1. Structural basis of peroxidase catalytic cycle of human Prdx6 Rimpy Kaur Chowhan, Hamidur Rahaman & Laishram Rajendrakumar Singh, Scientific Reports, 2020, 10, 17416.

  1. An in silico approach to identify potential medicinal plants for treating Alzheimer disease: a case study with acetylcholinesterase. Angamba Meetei Potshangbam, Apana Nandeibam, Thongamba Amom, Nongdam Potshangbam, Hamidur Rahaman, Ravindranath Singh Rathore,  Laishram Rajendrakumar Singh & Aslam Khan . Journal of Biomolecular Structure and Dynamics, 06 Oct 2020.

  1. pH induced conformational alteration in human peroxiredoxin 6 might be responsible for its resistance against lysosomal pH or high temperature. Rimpy Kaur Chowhan, Sunaina Hotumalani, Hamidur Rahaman & Laishram Rajendrakumar Singh. Scientific Reports. , 11, 9657 (2021).

  2. Structural and Functional Characterization of Covalently Modified Proteins Formed By a Glycating Agent, GlyoxalGurumayum Suraj Sharma, Reshmee Bhattacharya, Snigdha Krishna, Suliman Y. Alomar, Afrah F. Alkhuriji, Marina Warepam, Kritika Kumari, Hamidur Rahaman, and Laishram Rajendrakumar Singh. ACS Omega (2021) 6, 32, 20887–20894

  1. Peroxiredoxin-6 is a Guardian of lung pathophysiologies.Anju Kumari, Rimpy Kaur Chowhan, Pushpa Kakchingtabam, Sharifun Shahnaj,Hamidur Rahaman, Mohd Saquib Ansari, Laishram Rajendrakumar Singh- Current Protein & Peptide Science, 22, November 2021

 

Book Published

 

Pharmacological Chaperones in Protein Aggregation Disorder by Rahaman, H. et al., a chapter published in Springer published Book entitled Proteostasis and Chaperone Surveillance edited by Singh, Laishram Rajendrakumar in 2016.

 

 

Presentation and Conferences

  1. Participated at the National Symposium on Stability and Stabilization of Biomolecules (March 13-14, 2001) organized by Interdisplinary Biotechnology Unit,Aligarh Muslim University, Aligarh, India.

 

  1. Participated at BIF Training Program ‘Database and Data mining in Bioinformatics (Nov 14-16, 2007) Department of Computer Science, Jamia Millia Islamia, New Delhi, India.

  2. Participated at Interdisplinary science Conference-2007 on Recent Trends in Research in Biological Sciences held on Dec 7, 2007, CIRBSc, JamiaMilliaIslamia, New Delhi, India.

  3. Poster Presentation at National Symposium on Advances in Clinical Biochemistry-Biomarkers, Molecular Diagnosis and Quality Assurances & UPACBICON (Nov 15-16, 2008) organised by Dept. Of Biochemistry, Faculty of medicine, JNMC, Aligarh Muslim University, Aligarh, India.

“Sequence and stability of the goat cytochrome c”, Hamidur Rahaman, Md Khurshid Alam Khan and Faizan Ahmad.

 

  1. Participated at Interdisplinary science Conference-2008 Mathematics in Biology held on 2008, CIRBSc, JamiaMilliaIslamia, New Delhi, India.

  2. Poster Presentation at Experimental Biology 2011, Washington DC

“Phosphorylation ofperoxoredoxin6 changes its conformational and increase its binding to phospholipids”, HamidurRahaman, Suiping Zhou, Tea Shuvaeva, Sheldon I. Feinstein and Aron B. Fisher.

 

  1. Poster Presentation at RRR 2011, University of Pennsylvania Perelman School of Medicine, Philadelphia

“Phosphorylation of Prdx6 mediated by MAPkinase induces conformational change with concomitant increase in its phospholipase A2 acitivity”, HamidurRahaman, Suiping Zhou, Tea Shuvaeva, Sheldon I. Feinstein and Aron B. Fisher.

 

  1. Poster Presentation at Experimental Biology 2012, san diego, California. “Increased Phospholipase A2 Activity with Phosphorylation of Peroxiredoxin 6 Requires a Conformational Change in the Protein.”Hamidur Rahaman, Suiping Zhou, Tea Shuvaeva, Sheldon I. Feinstein and Aron B. Fisher.

  2. Participated as resource person at National Symposium on “Frontiers of Biophysics, Biotechnology & Bioinformatics” & 37th Annual Meeting of Indian Biophysical Society (IBS) January 13-16, 2013.

  3. Oral presentation at National Conference on Recent Trends in Protein Structural Biology-2013 (NCRTPSB-2013) December 16-18, 2013.

  4. Oral presentation at National Conference on Protein Structure and Dynamics in Health and Agriculture, November 3-4, 2017.

 

List of cDNA sequences submitted to GenBank

 

(1) Capra hircus mitochondrial cytochrome c mRNA, partial cds; nuclear gene for mitochondrial produc, ACCESSION No. DQ176429, NCBI Genbank, Rahaman,M.H., Baskar Singh,S., Srinivasan,A., Ahmad,F., Baig, M.A. And Singh,T.P.

 

 

Award and Honors.

  1. Qualified National eligibility Test (NET) July 2003, for Lectureship and Junior Research Fellow in Indian Universities (JRF-UGC) in Life Sciences.

  2. UGC-JRF at JamiaMilliaIslamia (2004-2006)

  3. UGC-SRF at JamiaMilliaIslamia (2006-2009)

  4. Awarded second best poster presentation award at RRR 2011, University of Pennsylvania, Philadelphia

  5. Summer Research Fellowship award by Indian Academy of Sciences, Bangalore, 2017

  6. Selected for Networking and Collaborative research at IIT Guwahati for Collaborative Research work, 2022

 

 

List of Research projects undertaken

 

  1. Mechanism of allosteric regulation of a unique bifunctional antioxidant enzyme Peroxiredoxin 6 on post-translational modification. Role: PI, Funding Agency: DBT, Government of India, Amount: 54.53 lakhs, Duration: 2013-2016.

 

  1. Protein covalent modification by homocysteine: Understanding the reactivity, toxicity, structural and functional consequences. Role: PI, Funding Agency: DBT, Government of India, Amount: 46.30 lakhs, Duration: 2017-2020.

 

  1. Evolution and transmission of drug-resistance tuberculosis in Agartala, Kohima and Imphal population. Role: Co-PI, Funding agency: DBT, Government of India, Amount: 87 lakhs, Duration: 2018-2021.

 

  1. DNA methylation analysis of OPRM1 and DAT1 genes in drug dependent population of Manipur-a population-based association study. Role Co-PI, Funding agency: ICMR, Government of India, Amount: 69.4 lakhs, Duration: 2019-20212.

 

 

List of PhD/RA students (Guiding/Guided)

PhD SCHOLARS:

  1. Ms. Sharifun Shahnaj

  2. Ms.Pushpa Kakchingtabam, DST-Inspire Fellow

  3. Mr. Mohd Ajmal, CSIR-JRF

  4. Mr. Wungnaopam N, CSIR-JRF

  5. Japani L., DST-Inspire Fellow

RESEARCH ASSOCIATE:

  1. Dr. Marina Warepam (ICMR-RA)

  2. Dr. Kh. Herojit Singh, (DBT-RA)

 

Number of BSc/MSc students (Guided)

26

Member of Scientific Society

  1. Society of Biological Chemists, India( SBC)

  2. Indian Biophysical Society, India (IBS)

  3. Indian Science Congress Association, India (ISCA)

 

 

 

 

 

 

sd/-

(Dr. Hamidur Rahaman)

Assistant Professor

Department of Biotechnology

Manipur University Canchipur

Imphal, Manipur, India-795003

E-mail: hamidur2006 [AT] gmail.com

rahamanh [AT] manipuruniv.ac.in

Tel: +91-9863518139/7005408775